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The interaction of only 2 drugs is rarely the concern; more often, patients are taking 3 or more medications that could influence interactions.

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Ritonavir (Norvir) is the most frequent inhibitor of this enzyme, while indinavir (Crixivan) and nelfinavir (Viracept) have fewer effects on CYP34, and saquinavir (Invirase) affects it even less.

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If one drug binds to another, neither may be absorbed at all.

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